Glycine catalyzed convenient synthesis of 2-amino-4H-chromenes in aqueous medium under sonic condition.
نویسندگان
چکیده
A one-pot three-component condensation of an aldehyde, malononitrile, and resorcinol has been achieved by ultrasound method. The reaction has been catalyzed by glycine in aqueous medium. This protocol afforded corresponding 2-amino-4H-chromenes in shorter reaction times, high yields and simple work-up procedures with the green aspects by avoiding toxic reagents.
منابع مشابه
Green and Efficient One-Pot Synthesis of 2-Amino-3-phenylsulphonyl-4H-chromenes under Solvent-Free Conditions
A green and convenient method for the synthesis of 2-amino-3-phenylsulphonyl-4H-chromenes by a one-pot three-component condensation of 1-naphthol, phenylsulphonylacetonitrile and aromatic aldehydes under solvent-free conditions using potassium phosphate tribasic trihydrate as an efficient catalyst is described. The reaction of 1-naphthol with phenylsulphonylacetonitrile and various aromatic...
متن کاملEfficient and Eco-Friendly Procedure for the Synthesis of 2-Amino-4H-Chromenes Catalyzed by Diammonium Hydrogen Phosphate
An efficient and eco-friendly protocol for the preparation of 2-amino-4H-chromenes employing a multi-component, one-pot condensation reaction between aromatic aldehydes, malononitrile and1-naphthol has been developed. The reaction of 1-naphthol with malononitrile and various aromatic aldehydes was carried out i...
متن کاملLactic acid-catalyzed Eco-friendly Cyclization Reaction for the Synthesis of 4H-benzo[b]pyrans and 3,4-dihydropyrano[c]chromenes in EtOH/H2O as an Efficient Green Reaction Medium
An environmentally friendly, green, and highly efficient process for the synthesis of biologically and pharmacologically 4H-benzo[b]pyrans and 3,4-dihydropyrano [c] chromenes is developed by condensing cyclic aromatic aldehydes, malononitrile, and dimedone or 4‐hydroxycoumarin in the presence of lactic acid as an efficient and green catalyst. The corresponding products have b...
متن کاملA green approach for the synthesis of 2-amino-4H-chromene derivatives using Polystyrene-Supported 1-Methylimidazolium tetrachloroferrate as an efficient heterogeneous catalyst in water
In this study, we reported facile and efficient synthesis of 2-amino-4H-chromenes that catalyzed by polystyrene-supported 1-methylimidazolium tetrachloroferrateas. The synthesis proceeds with various aldehydes under mild conditions and afford the target products with good to high yields.
متن کاملOne-pot three component synthesis of 2-amino-4H-chromenes under green and high efficient conditions
A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Ultrasonics sonochemistry
دوره 19 4 شماره
صفحات -
تاریخ انتشار 2012